Zolpidem maintained an orderly spaced within-day pattern of injections and daily rates of self-injection were higher than saline i. Daily rates of zolpidem self-injection were relatively stable in two baboons, and increased over time in the third baboon. Substitution of saline for zolpidem produced a rapid decrease in responding that remained low i.
Chronic self-injection of zolpidem produced an increase in responding maintained by food pellet delivery and an increase in body weights. Administration of flumazenil 0. Substitution of saline after chronic zolpidem self-injection produced a time-limited spontaneous withdrawal syndrome. Behavioral signs and postures were similar to those observed during flumazenil-precipitated withdrawal and were most prominent during the first 8 days after zolpidem was discontinued.
Therefore, like midazolam, zolpidem maintained self-injection and physical dependence developed under conditions of long-term continuous availability. This prescription sleeping medication comes in the form of a small, white, yellow, blue, or pink oblong pill that is taken by mouth and has an extended-release effect. It is meant to help people fall asleep faster and stay asleep longer. However, some people crush and snort Ambien to produce stronger, more rapid effects.
The manufacturers of Ambien are notorious for their widespread marketing techniques, making the drug a household name as well as something that is frequently seen in popular culture. This sleep aid was originally marketed as a safer and less addictive alternative to benzodiazepines , however, users and physicians alike quickly realized the addictive qualities of the drug.
Even though this scheduling suggests rare recreational use, many users abuse Ambien by taking too high of a dose, snorting it, injecting it, or taking it to produce euphoric and hallucinogenic effects. Since the medication is habit-forming, it is typically only prescribed for short-term treatment of fewer than two weeks.
Zolpidem tartrate, the active ingredient in Ambien, works by increasing the relaxing effects of GABA — a neurotransmitter in the brain that is associated with insomnia, relaxation, anxiety, mood, and more. Although it is not a narcotic, the drug is a depressant that produces calming effects on the body, therefore, you can get high on Ambien if you abuse it.
If a person swallows Ambien, the high will set in around 30 minutes after taking the drug and last for several hours. If someone is snorting Ambien, the high may set in faster, but last for a shorter period of time. Some people who are addicted to Ambien will abuse it by injecting it intravenously for an even stronger, more powerful high.
When someone gets high on Ambien, they will feel extremely groggy, drowsy, and euphoric. They may also begin to have auditory or visual hallucinations. Oftentimes, the effects of Ambien abuse will look similar to alcohol or benzodiazepine intoxication. Ambien abuse occurs in many different forms. For example, taking the drug without a prescription, purchasing the drug on the streets, taking a higher dose than what you are prescribed, or snorting or injecting Ambien are all forms of drug abuse.
Some people believe that Ambien is safer than some other benzodiazepines because there is a lower potential for overdose. While users may need to take more Ambien to overdose than they would other benzodiazepines, the signs and symptoms of an Ambien overdose are difficult to detect.
In most cases, the symptoms simply mirror those of Ambien intoxication. When taken in large doses, Ambien slows down breathing, heart rate, and other essential bodily functions. If an overdose occurs, it can lead to respiratory failure and death. If a person has taken Ambien and has seriously slowed or shallow breathing, they may be experiencing an overdose. Another danger that is commonly associated with Ambien abuse is the potential for risky and dangerous unconscious behavior.
For example, sleepwalking, memory problems, sleep eating, sleep-driving, and changes in behavior are all common side effects of taking Ambien. One popular way in which Ambien is abused is by mixing the substance with alcohol.
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